Email to a colleague
View Printer Friendly           Home | Other Research | 2007 Summer Fellowship Opportunity

Current Medical Student Summer Research Fellows

·	Current Medical Student Research Fellows

Amandip Singh Gill Preceptor: Devin Binder, MD, PhD Institution: University of California – Irvine Amandip Gill is currently working in the laboratory of Dr. Devin K. Binder, who along with others is marshaling strong evidence implicating glial cells in the development of epilepsy. Epilepsy, affecting approximately 1% of the population, is controlled by current antiepileptic drugs in only ~70% of patients. These medications often act as general CNS depressants and lead to marked inhibitory effects on cognition and development. Recent studies have begun to elucidate novel roles and molecular mechanisms of glial cell involvement in epileptogenesis. Amandip’s project deals with the role of aquaporins on CNS glia that have recently been shown to have powerful effects on neural signal transduction. Amandip is studying the role of aquaporin-4, the primary CNS glial water channel, in mouse models of epileptogenesis. This series of studies may lead to the identification of novel molecular targets and possibly an entirely new category of antiepileptic drugs with fewer side effects than current therapies.