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Abstract Details

AbstractDetails

Abstract Date: 5/1/2016

Author(s):
Jeremy Steinberger, MD
Nathan Lee, BA
Parth Kothari, BA
Ahmed Awad, MD
Christopher Sarkiss, MD
eric oermann, MD
John Caridi, MD
Raj Shrivastava, MD (New York, NY)

Introduction:

Large scale studies examining the effect of age on outcomes after meningioma surgery have not been performed to date. This study utilizes a large national database to assess the impact of age in adults undergoing surgery for meningioma.

Methods:

Patients were identified by CPT code in the NSQIP database. Univariate analysis was performed to compare demographics, comorbidities, and postoperative complications in patients of different ages.  Multivariate step-wise logistic regression was performed on each complication that demonstrated significant association with age in the univariate comparison. 

Results:

1,568 patients were identified in the database.  On univariate analysis, patients under 50 had overall complication rates of 17.9%, while patients 71-80 had rates of 29.6% and patients above 80 had rates of 31.2% (p<0.0001).  Specifically, patients in the 71-80 group and >80 group had higher rates of pulmonary complications, deep venous thromboses/pulmonary embolisms, and urinary tract infections. Patients under 50 had a length of stay greater than 5 days 32.3% of the time, while patients 71-80 and >80 had rates were 49.2% and 64.5%, respectively (p<0.0001) . Age had a significant impact on mortality. Patients under 50 had a 30-day mortality rate of 0.7%, while patients 71-80 had mortality rates of 2.5% and patients >80 had mortality rates of 8.6% (p<0.0001).  On multivariate analysis, patients greater than 80 were at higher risk of overall complications (Adjusted OR 2.37, 95% CI 1.30-4.36, p=0.015) and prolonged length of stay (Adjusted OR 3.154, 95% CI 1.78-5.58, p=0.0002). Death within 30 days was greater than 15 times higher in patients >80 than the younger groups (Adjusted OR 15.7, 95% CI 3.03-81.0, p<0.0001).


Conclusion:

In evaluating the effect of age in 1,568 patients undergoing meningioma surgery, 80 years old seems to be the statistical cut off for significantly increased morbidity and mortality.

Keywords:

Article ID: AA-34820


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